The island of Samos is located at the most eastern point of the Aegean Sea, close to the coast of Asia Minor. The port of Pythagorio, birthplace of the philosopher and mathematician Pythagoras, lies at the southeastern point of the island. Due to its geographical location it was the most important port of the Mediterranean Sea in antiquity.
It is the first and last port opposite of Ephesus in Asia Minor, where the famous the Silk Road ended. Here the West was connected with Mesopotamia and the Far East. This was the main reason why it was the first port to be constructed in the 6th century BC. Herodotus referred to it as: “The big wall in the sea”. Today the Marina of Pythagorio stands as a very important location in the Aegean Sea.